^DIn the year of our lord ^Deighteen hundred ^Aand ^Geleven ^HmiOn March the seventeenth ^Aday ^DI will raise up a beer and I'll ^Draise ^Aup a ^Gcheer ^HmiFor Saccharomyces ^Acerevisiae^{G D G}Here's to ^Dbrewers yeast, ^Athat humblest of all ^Gbeasts ^GProducing carbon ^Dgas reducing ^Gacetalde^Ahyde ^GBut my friends that isn't ^Dall -- it makes ^Hmiethyl alco^Ghol ^GThat is what the ^Dyeast excretes and ^Athat's what we imbi^Dbe ^GAnaerobic ^Disolation ^AAlcoholic ^Hmifermentation ^GNADH ^Doxidation ^AGive me a beer^{D CHORUS G D A Hmi A G D A D} Li-Diddly-I My intestinal wall absorbs that ethanol And soon it passes through my blood-brain barrier There's a girl in the next seat who I didn't think that sweet But after a few drinks I want to marry her I guess it's not surprising, my dopamine is rising And my glutamate receptors are all shot I'd surely be bemoaning all the extra serotonin But my judgment is impaired and my confidence is not Allosteric modulation No Long Term Potentiation Hastens my inebriation Give me a beer ^CHORUS Li-Diddly-I When ethanol is in me, some shows up in my kidneys And inhibits vasopressin by degrees A decrease in aquaporins hinders water re-absorption And pretty soon I really have to pee Well my liver breaks it down so my body can rebound By my store of glycogen is soon depleted And tomorrow when I'm sober I will also be hungover Cause I flushed electrolytes that my nerves and muscles needed Diuretic activation Urination urination Urination dehydration Give me a beer